I suggesst you start with DMT, the active ingredient of Ayahuasca. DMT is easily metabolised by your body, but Ayahuasca contains chemicals that block the enzymes which process DMT making it last for hours. DMT only lasts maybe 5-30mins depending on the person, but its pretty much exactly like Ayahusca. Think of DMT as a trailer to Ayahuasca the movie.