DarkRP without BitMiners/Printers?

In my opinion that'll just make it harder to earn money and you lose the point of defending your base, IE meth if that gets blown up wow wee you just need to rebuy everything.

this seems like a really difficult thing to pull off since that's where most of the economy comes from

I agree with the others, printing has always been the most beneficial way to earn money and it will most likely stay that way when it comes to RP.

No printers in my opinion would benefit RP servers in many ways. MonolithRP is a great example.